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Current Science Article: Stem Cell Research in the Spotlight Once Again

Recent discoveries about the role of stemproblem. Interviewed by Vision Magazine at
cells in cancer have altered the landscape ofthe Stem Cells World Congress earlier this
cancer research, says Medical News Today.year in La Jolla, California, veterinarian
There is, however, a long-runningand CEO of Vet-Stem, Robert Harmon, explained
philosophical rift over stem cell research athow his company is currently providing stem
both the state and federal levels. Somecell therapies for animals. Injected into an
groups would rather focus on adult stem cellinjury or degenerated tissue, the stem cell
research, avoiding the moral and ethicaltreatment evokes healing in unprecedented
questions about research involving embryos.ways. As it has been since its discovery
While ethical debate on human embryonic stemalmost 400 years ago, the cell and the "vital
cells will continue, much more is occurringforce" that makes it the seat of biological
on the rings surrounding this bull's-eyelife continues to hold attention. It is
issue, including research in both druglikely that there will be no end to the moral
development and adult stem cells. Biologists'and ethical questions and investigations.
understanding of new sources and uses ofToday's new age of molecular understanding,
adult and nonembryonic stem cells isgenomics, proteomics, gene splicing and
advancing rapidly. Called "niches" orbioengineering is barely underway. It is not
"crypts," it seems that almost anyplace onesurprising, then, that the more we know, the
looks in the body (nose, eye, hair follicle,more we recognize how little we understand.
intestine, bone marrow, central nervousThe timeline of discovery has been
system), stem cells are being found. Fromexponential: from discovery of the DNA double
such basic knowledge, it has been reportedhelix in 1953, and the understanding of the
that successful animal and human therapygenetic code, gene splicing and cell
using patient stem cells is alreadydifferentiation in the 60s, 70s and 80s,
occurring. As more stem cell crypts arescience rapidly jumped up the learning curve
discovered, the desire to understand how toto the cloning of whole organisms and the
manipulate them within the body only becomesdiscovery of embryonic stem cells less than a
more acute. At the 2007 Annual Meeting of thedecade ago. The future possibilities for the
American Association for Cancer Research,application of this knowledge seem enormous.
researchers presented new discoveries aboutRead the full article about Stem Cell
stem cells in leukemia, breast and colonResearch and interviews with speakers at the
cancer that add to the growing evidence thatStem Cells World Conference at Vision.org.
perhaps cancer is, fundamentally, a stem cell



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